Two graduates of the Data Science Institute (DSI) at Columbia University are using computational design to quickly discover treatments for the coronavirus.
Andrew Satz and Brett Averso are chief executive officer and chief technology officer, respectively, of EVQLV, a startup creating algorithms capable of computationally generating, screening, and optimizing hundreds of millions of therapeutic antibodies. They apply their technology to discover treatments most likely to help those infected by the virus responsible for COVID-19. The machine learning algorithms rapidly screen for therapeutic antibodies with a high probability of success.
Conducting antibody discovery in a laboratory typically takes years; it takes just a week for the algorithms to identify antibodies that can fight against the virus. Expediting the development of a treatment that could help infected people is critical says Satz, who is a 2018 DSI alumnus and 2015 graduate of Columbia’s School of General Studies.